منابع مشابه
Chromosome arrangement within a bacterium
BACKGROUND The contour length of the circular chromosome of bacteria is greater than a millimeter but must be accommodated within a cell that is only a few micrometers in length. Bacteria do not have nucleosomes and little is known about the arrangement of the chromosome inside a prokaryotic cell. RESULTS We have investigated the arrangement of chromosomal DNA within the bacterium Bacillus su...
متن کاملMacromolecular arrangement within muscle.
Electron microscopy has already given much information about the macromolecular components of striated muscle (1, 4). Thus it is shown that myofibrils of teased muscle are ribbons composed of parallel arrays of filaments associated with an amount of seemingly amorphous material that is great,est in the anisotropic regions. For the present work, strips of psoas muscle separated from a rabbit at ...
متن کاملArrangement of L2 within the papillomavirus capsid.
Papillomaviruses are a family of nonenveloped DNA tumor viruses. Some sexually transmitted human papillomavirus (HPV) types, including HPV type 16 (HPV16), cause cancer of the uterine cervix. Papillomaviruses encode two capsid proteins, L1 and L2. The major capsid protein, L1, can assemble spontaneously into a 72-pentamer icosahedral structure that closely resembles native virions. Although the...
متن کاملTracking of Chromosome and Replisome Dynamics in Myxococcus xanthus Reveals a Novel Chromosome Arrangement
Cells closely coordinate cell division with chromosome replication and segregation; however, the mechanisms responsible for this coordination still remain largely unknown. Here, we analyzed the spatial arrangement and temporal dynamics of the 9.1 Mb circular chromosome in the rod-shaped cells of Myxococcus xanthus. For chromosome segregation, M. xanthus uses a parABS system, which is essential,...
متن کاملReal-time RNA profiling within a single bacterium.
Characterizing the dynamics of specific RNA levels requires real-time RNA profiling in a single cell. We show that the combination of a synthetic modular genetic system with fluorescence correlation spectroscopy allows us to directly measure in real time the activity of any specific promoter in prokaryotes. Using a simple inducible gene expression system, we found that induced RNA levels within...
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ژورنال
عنوان ژورنال: Current Biology
سال: 1998
ISSN: 0960-9822
DOI: 10.1016/s0960-9822(98)70464-6